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Dr. Buxbaum is Director of the Cognition and Action Laboratory at the Moss Rehabilitation Research Institute and an Associate Professor of Rehabilitation Medicine at Thomas Jefferson University. She holds a Psy.D. in Psychology with a specialization in clinical neuropsychology, and has post-doctoral training in experimental cognitive neuropsychology. She has received funding from the NIH, NIDRR, and James S. McDonnell Foundation.

Areas of Expertise

• Skilled action in healthy participants and disorders of skilled action following stroke and corticobasal degeneration, including underlying neuropathology, nature of representations for object use, relationship of action knowledge to semantic knowledge systems, naturalistic action, relationship to putative “mirror neuron” systems, status of internal models for action planning, coding of hand-object interactions, and spatio-motor frames of reference for action.
• Hemispatial neglect, including neuroanatomical substrate, patterns and subtypes of neglect, recovery, innovative treatments for neglect, e.g., prism treatment and virtual reality, and clinical barriers to effective treatment.
• Cognitive neuropsychology research methods, including designing experiments with impaired populations, single case designs, and hypothesis-driven lesion analysis techniques.

Programs of Research

• Use of behavioral and fMRI methods to explore the nature and neuroanatomic substrate of the skilled action system
• Exploration of the factors underlying deficits in complex naturalistic action

• Assessment and treatment of hemispatial neglect

Publications

• Buxbaum LJ, Kyle KM, Tang K, Detre JA. Neural substrates of knowledge of hand postures for object grasping and functional object use: Evidence from fMRI. Brain Res. 2006 Sep 6; PMID 16962075
• Buxbaum LJ, Coslett HB. Neglect of chimeric figures: Two halves are better than a whole. Neuropsychologia 32, 275-288, 1994 PMID 8202223
• Buxbaum LJ, Schwartz MF, Coslett HB, Carew TG. Naturalistic action and praxis in callosal apraxia. Neurocase 1, 3-17, 1995 PMID 11788737
• Buxbaum LJ, Coslett HB, Montgomery MW, Farah MJ. Mental rotation may underlie apparent object-based neglect. Neuropsychologia 34, 113-126, 1996 PMID 8852874
• Buxbaum LJ, Schwartz MF, Carew TG. The role of semantic memory in object use. Cognitive Neuropsychology 14(2), 219-254, 1997
• Buxbaum LJ, Coslett HB. Subtypes of optic ataxia: Reframing the disconnection account. Neurocase 3, 159-166, 1997
• Farah MJ, Buxbaum LJ. Object-based attention in visual neglect: Distinguishing among “object-based” hypotheses. In Karnath, H.O. & Thier, P. (eds.) The Parietal Lobe Contribution to Orientation in 3D Space. 1997
• Schwartz MF, Buxbaum LJ. Naturalistic action. In Rothi, L.G. & Heilman, K.M. (eds.) Apraxia: The Neuropsychology of Action. Lawrence Erlbaum Associates, 1997
• Schwartz MF, Montgomery MW, Buxbaum LJ, Lee SS, Carew TG, Coslett HB, Ferraro M, Fitzpatrick-DeSalme E, Hart T, Mayer N. Naturalistic action impairment in closed head injury. Neuropsychology, 12(1): 13-28,1998 PMID 9460731
• Buxbaum LJ, Coslett HB. Spatio-motor representations in reaching: Evidence for subtypes of optic ataxia. Cognitive Neuropsychology, 15(3): 279-312,1998
• Buxbaum LJ, Schwartz MF, Montgomery MW. Ideational apraxia and naturalistic action. Cognitive Neuropsychology, 15(6-8), 617-643, 1998
• Schwartz MF, Buxbaum LJ, Montgomery MW, Ferraro M, Fitzpatrick-DeSalme E, Hart T, Lee SS, Coslett HB. Naturalistic action impairment following right hemisphere stroke. Neuropsychologia, 37: 51-66, 1999 PMID 9920471
• Buxbaum LJ, Veramonti T, Schwartz MF. Function and manipulation tool knowledge in apraxia: Knowing ‘what for’ but not ‘how’. Neurocase, 6, 83-97, 2000.
• Buxbaum LJ, Giovannetti TG, Libon D. The role of the dynamic body schema in praxis: Evidence from primary progressive apraxia. Brain and Cognition, 44, 166-191, 2000. PMID 11041988
• Buxbaum LJ., Coslett, HB. Specialized structural descriptions for human body parts: Evidence from autotopagnosia. Cognitive Neuropsychology, 18(4), 363-381, 2001.
• Schwoebel, J., Coslett, H.B., Buxbaum, LJ. Compensatory coding of body-part location in autotopagnosia: Evidence for extrinsic egocentric coding. Cognitive Neuropsychology, 18(4), 363-381, 2001.
• Buxbaum, LJ. Ideomotor apraxia: A call to action. Neurocase, 7, 445-58, 2001. PMID 11788737
• Buxbaum, LJ, Permaul, P. Hand-centered attentional and motor asymmetries in unilateral neglect. Neuropsychologia, 39, 653-664, 2001. PMID 11311296
• Buxbaum, LJ.,Coslett, HB. Spatio-Motor Aspects of Action. In B. Rapp (Ed.), The Handbook of Cognitive Neuropsychology. 543-563. Philadelphia: Psychology Press, 2001.
• Coslett, HB, Buxbaum, LJ. Treatment of Neglect. In J. Noseworthy (Ed.), Neurological Therapeutics: Principles and Practice. London: Martin Dunitz, 2002.
• Schwartz, MF. Buxbaum, LJ., Ferrraro, M., Veramonti, T., Segal, M. The Naturalistic Action Test: Bury St. Edmunds, England: Thames Valley Test Co., 2002.
• Pierce, S., Buxbaum, LJ. Treatments of unilateral neglect: A review. Archives of Physical Medicine and Rehabilitation, 83,256-68, 2002. PMID 11833032
• Giovannetti, T, Libon, D, Buxbaum, LJ., and Schwartz, M.F. Naturalistic action impairment in dementia. Neuropsychologia, 40, 1220-1232, 2002. PMID 11931925
• Pavese, A., Coslett, HB, Saffran, EM, Buxbaum, LJ. Limitations of attentional orienting: Effects of abrupt visual onsets and offsets on naming two objects in a patient with bilateral posterior lesions. Neuropsychologia, 40, 1097-1103, 2002. PMID 11900760
• Pavese, A., Buxbaum, LJ. Action matters: The role of action plans and object affordances in selection for action. Visual Cognition, 9(4/5), 559-550, 2002.
• Buxbaum LJ, Saffran EM. The semantics of object manipulation and object function: A double dissociation. Brain and Language 82, 179-199, 2002 PMID 12096875
• Schwartz, MF, Segal, M, Veramonti, T, Ferraro, M, & Buxbaum, LJ. The Naturalistic Action Test. Neuropsychological Rehabilitation, 12(4), 311-339, 2002.
• Buxbaum, LJ, Sirigu, A, Schwartz, MF, Klatzky, R. Cognitive representations of hand posture in ideomotor apraxia. Neuropsychologia, 41, 1091-1113, 2003. PMID 12667544
• Sirigu, A., Daprati, E., Buxbaum, LJ. Giraux, P. How the human brain represents gestures: Effects of brain damage. In S. Johnson (Ed.), Cognitive Neuroscience Perspectives on the Problem of Intentional Action. Cambridge, MA: MIT Press, 2003.
• Schwoebel, J, Buxbaum, LJ, Coslett, HB. Representations of the human body in the production and imitation of complex movements. Cognitive Neuropsychology, 21 (2/3/4), 285-298, 2004.
• Coslett, HB Buxbaum, LJ. The planning-control model and spatio-motor deficits following brain damage. Comment on Glover, S. Separate visual representations in the planning and control of action. Behavioral and Brain Sciences, 27(1), 31-32, 2004.
• Buxbaum, LJ, Ferraro, MK, Veramonti, T, Farnè, A, Whyte, J, Ladavas, E, Frassinetti, F, Coslett, HB. Hemispatial neglect: subtypes, neuroanatomy, and disability. Neurology, 62, 749-765, 2004. PMID 15007125
• Farnè, A., Buxbaum, LJ., Ferraro, M., Frassinetti, F., Whyte, J., Veramonti, T., Angeli, V., Coslett, H.B., Làdavas, E. Patterns of spontaneous recovery of neglect and associated disorders in acute right brain-damaged patients. Journal of Neurology, Neurosurgery, and Psychiatry, 75, 1401-1410, 2004. PMID 15377685
• Giovannetti, T, Buxbaum, LJ, Chatterjee, A., Biran, I. Reduced endogenous control in anarchic hand syndrome: Evidence from naturalistic action. Neuropsychologia, 43, 75-88, 2005. PMID 15488908
• Buxbaum, LJ, Johnson, SH, Bartlett-Williams, M. Deficient internal models for planning hand-object interactions in ideomotor apraxia. Neuropsychologia, 43(6), 917-929, 2005. PMID 15716162
• Boronat, C., Buxbaum, LJ, Coslett, HB, Tang, K, Saffran, EM, Kimberg, DY, Detre, JA. Distinctions between function and manipulation knowledge of objects: Evidence from functional magnetic resonance imaging. Cognitive Brain Research, 23(2-3), 361-373, 2005. PMID 15820643
• Buxbaum, LJ, Kyle, K, Menon R. On beyond mirror neurons: Internal representations subserving imitation and recognition of skilled object-related actions in humans. Cognitive Brain Research, 25(1), 226-239, 2005. PMID 15996857
• Buxbaum, LJ. On the right (and left) track: Twenty years of progress in studying hemispatial neglect. Cognitive Neuropsychology, 23(1), 184-201, 2006
• Biran, I., Giovannetti, T, Buxbaum LJ, Chatterjee A. The alien hand syndrome: what makes the alien hand alien? Cognitive Neuropsychology, 23(4), 563-582, 2006.
• Buxbaum, LJ, Kyle, KM, Grossman, M, Coslett, HB. Left inferior parietal representations for skilled hand-object interactions: Evidence from stroke and corticobasal degeneration. Cortex, In Press.
• Buxbaum, LJ, Ferraro, M, Whyte, J, Coslett, HB, Gershkoff, A. Amantadine treatment of hemispatial neglect: a double-blind, placebo-controlled study. American Journal of Physical Medicine and Rehabilitation, In Press.
• Barrett, AM, Buxbaum, LJ, Coslett, HB, Heilman, KM, Hillis, AG, , Millberg, W. Cognitive rehabilitation interventions for neglect and related disorders: moving from bench to bedside in stroke patients. Journal of Cognitive Neuroscience, 18(7), 1223-1236, 2006. PMID 16839294
• McCrae, SM, Buxbaum, LJ, Coslett, HB. Illusory conjunctions in simultanagnosia: Course coding of visual feature location? Neuropsychologia, 44(10), 1724-36, 2006. PMID 16643968
• Jax, S., Buxbaum, LJ, Moll, A. Deficits in movement planning and intrinsic coordinate control in ideomotor apraxia. Journal of Cognitive Neuroscience, In Press.