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Dr. Coslett is Professor of Neurology at the University of Pennsylvania and a long-time consultant to the Moss Rehabilitation Research Institute. He is trained in Neurology with specialization in Behavioral Neurology. He has received funding from the NINDS, NIMH, NIDCD and private foundations for his research.

Areas of Expertise

• Visuo-spatial attention including Neglect and the Balint syndromes. Areas of interest include the cognitive neuropsychology of attention, mechanisms underlying clinical disorders such as neglect and treatment of neglect and related disorders.
• Normal and abnormal processing of temporal information. We are investigating the brain mechanisms and anatomic basis of the perception of time in normal and clinical populations. Methodologies include Transcranial Magnetic Stimulation, fMRI and behavioral studies in normal and brain lesion subjects.
• Role of TMS in the treatment of chronic aphasia. This on-going investigation explores the use of 1 Hz. Repetitive TMS over the right hemisphere as a treatment for aphasia resulting from strokes. The anatomic basis of the improvement is also assessed with fMRI.
• Motor control and its breakdown in brain lesions. This line of research explores the anatomic basis and functional architecture of the motor control system using behavioral studies in normal and brain lesion subjects.

Programs of Research

• TMS in the treatment of chronic aphasia
• Behavioral studies of the architecture and anatomic bases of motor control
• fMRI, TMS and behavioral investigations of normal and abnormal time processing
• Investigations of the anatomic basis of aphasia using developing techniques in voxel-based morphometry
• Mental motor imagery as a measure of pain severity

Publications

• B Hamilton RH, Coslett HB, Buxbaum L, Whyte J, Farne A, Frassinetti F, Ferraro M. "Inconsistency of Neglect Subtypes in Patients after Acute Right Hemisphere Stroke." JINS 14: 23-32, 2008. PMID 18078528
• Coslett HB, Lie E. "Simultanagnosia: When a rose is not red." J Cognitive Neuroscience. 20: 36-48, 2008.
• Wiener M, Coslett HB. "Disruption of temporal processing in a patient with Fronto-temporal Dementia." Neuropsychologia 46: 1927-1939, 2008. PMID 18329055
• Coslett HB, Lie E. "Simultanagnosia: Semantic category and repetition blindness." Neuropsychologia 46: 1853-1863, 2008. PMID 18514677
• Coslett HB, Buxbaum LJ, Schwoebel. "Accurate Reaching after Active but not Passive Movements of the Hand: Evidence for Forward Modeling." Behavioural Neurology 19(3): 117-25, 2008. PMID 18641431
• Hamilton, AC, Coslett HB. "Refractory Access Disorders and the Organization of Concrete and Abstract Semantics: Do they differ?" Neurocase 14(2):131-40, 2008. PMID 18569737
• Hamilton, AC, Coslett, HB. "Role of Inflectional Regularity and Semantic Transparency in Reading Morphologically Complex Words: Evidence from Two Phonologic Dyslexics." Neurocase, In press.
• Jax, S, Buxbaum, LB, Coslett, HB. "More than (where the target) meets the eyes: Disrupted visuomotor transformations in optic ataxia." Neuropsychologia 47: 230-238, 2009. PMID 18725238
• Schnur, T, Schwartz MF, Kimberg DY, Hirshorn, E, Coslett HB, Thompson-Schill, SL. "Localizing interference during naming: Convergent neuroimaging and neuropsychological evidence for the function of Broca's area." PNAS 106: 322-327, 2009. PMID 19118194
• Coslett, HB, Shenton, J, Dyer, T, Wiener, M. "Cognitive Timing: Neuropsychology and anatomic basis." Exp. Brain Res.: In press.
• Wiener, M, Hamilton, RH, Matell, M, Turkeltaub, P, Coslett, HB. "Fast forward: Supramarginal gyrus stimulation alters time measurement." J. Cogn. Neurosci.: In press.
• Medina, J, Jax, S, Coslett HB. "Two-component models of reaching: Evidence from deafferentation in a Fitts'Law task." Neuroscience Letters: In press.
• Hamilton, RH, Stark, M, Coslett HB. "Increased Effect of Target Eccentricity on Covert Shifts of Visual Attention in Patients with Neglect." Cortex: In press.
• Lie E, McCrae S, Coslett HB. (2006) "The Effect of Gaze Direction on Sound Localization in Brain-Injured and Normal Adults." Experimental Brain Research: 168(3): 322-336.
• Wolk D, Coslett HB, Glosser G. (2005) "The Role of Sensory-Motor Information in Object Recognition: Evidence from Category-specific Visual Agnosia." Brain and Language: 94(2): 131-146. PMID 15896389
• Schwoebel J, Coslett HB. (2005) Evidence for Multiple, Distinct Representations of the Human Body. J. Cog. Neurosci.: 17(4): 543-553. PMID 15829076
• Schwoebel J, Buxbaum LJ, Coslett HB. (2004) Representations of the human body in the production and imitation of complex movements. Cognitive Neuropsychology 21: 285-298.
• Coslett HB. (1997) "Neglect in vision and visual imagery: A double dissociation". Brain 120: 1163-1171. PMID 9236629
• Coslett HB, Monsul N. (1994) "Reading with the right hemisphere: Evidence from Transcranial Magnetic Stimulation." Brain and Language 46: 198-211. PMID 8137142
• Coslett HB. (1999) Spatial Influences on Motor and Language Function. Neuropsychologia 37: 695-706. PMID 10390031
• Coslett HB, Lie E. Bare Hands and Attention: Evidence for a tactile representation of the human body. Neuropsychologia 42: 1865-1876, 2004. PMID 15381016
• Schwartz, M.F., Kimberg, D.Y., Walker, G.M., Faseyitan, O., Brecher, A., Dell, G.S., & Coslett, H.B. (2009). Anterior temporal involvement in semantic word retrieval: voxel-based lesion-symptom mapping evidence from aphasia. Brain, 132 (12), 3411 - 3427.
  Brain - A Journal of Neurology (PDF: 17 pages)
  PMID 19942676